Airborne particle detection with selective thermophoretic particle deflection

ABSTRACT

A method for analyzing particles in an air stream includes concentrating the particles in an interior region of the air stream and deflecting the concentrated particles in the air stream with a generated thermal gradient. Smaller particles in the air stream may be selectively deflected away from the interior region and towards a periphery of the air stream at a different rate than larger particles in the air stream. The generated thermal gradient may be controlled to deflect particles in a selected particle size range onto a surface of a particle detector. An effective mass of the collected particles and an aerosol mass concentration estimate of the particles within the selected particle size range may be generated. Systems for analyzing particles are also disclosed.

CROSS-REFERENCE TO RELATED APPLICATIONS

This patent application claims priority to U.S. Provisional Patent Applications. 62/586,130; 62/586,134; 62/586,141; 62/586,143; and 62/586,148; all filed on Nov. 14, 2017; the entire contents of each are hereby incorporated herein by reference.

TECHNICAL FIELD

This patent disclosure relates generally to the field of particulate-matter detection and more specifically to air-quality sensors and to systems and methods for determining airborne-particle content.

BACKGROUND

The presence of airborne and other gas-borne particulate matter (PM), alternatively referred to as aerosol particles, can contribute to poor air quality and potentially adverse health effects. These particles can penetrate into human and animal lungs, contributing to lung disease, heart disease, cancer, and other illnesses. Such particles may be produced by many sources, including industrial and agricultural processes, fossil-fuel combustion in power plants and vehicles, fires, smoking, and other natural and manmade causes.

Airborne particles with a diameter of 2.5 microns or less (often termed PM2.5) tend to be particularly problematic. These finer sized particulates can remain suspended in the air for long periods of time and can penetrate deep into the lung alveoli. Airborne particles under 0.1 microns in diameter can pass through the lungs and enter the body, causing damage to other organs. Particles of intermediate sizes, such as between 2.5 and 10 microns (often termed PM10), although not as potentially toxic as the smaller PM2.5 particles, are also medically problematic because these can also penetrate into at least the outer portions of the lungs. In contrast, the larger sized particles, such as particles over 10 microns in diameter, tend to be less problematic from a health perspective. This is because such larger particles do not penetrate as deeply into the lungs and tend to settle out of the air relatively quickly. The impact of nanoparticles in the range of 0.01 microns to 0.1 microns is relatively unknown and is an active area of study, although significant adverse health impacts are suspected.

Monitoring and controlling airborne particulate matter is of intense interest due to potentially adverse health and environmental effects. Various health, legal, government, scientific, industrial and commercial entities have considerable interest in methods of monitoring airborne and other gas-borne particulate matter. Methods that can further distinguish between various sizes of particulate material are particularly valued. Current systems for monitoring particulate matter tend to be relatively bulky, complex and expensive, which generally render them unsuitable for mass-market use.

Airborne particles can range greatly in size, shape, content and concentration. Methods and systems for selectively fractionating and separating airborne particles before particle detection and property determinations can provide benefits including reductions in the size, complexity and cost of such systems, improved device performance and detection rates, and lower limits of detection.

BRIEF SUMMARY OF THE INVENTION

In some embodiments, the invention may be a method for analyzing particles in an air stream includes concentrating particles in an interior region of the air stream and deflecting the concentrated particles in the air stream with a generated thermal gradient. Smaller particles in the air stream may be selectively deflected away from the interior region and towards a periphery of the air stream at a different rate than larger particles in the air stream.

The generated thermal gradient may be controlled to deflect particles in a selected particle size range onto a surface of a particle detector. The airstream velocity of the air stream may be controlled. Deflected particles within a selected particle size range may be collected on a surface of a particle detector. The selected particle size range may include a particle size range between about 0.01 microns and 0.1 microns, 0.01 microns and 0.3 microns, 0.1 microns and 1.0 microns, 1.0 microns and 2.5 microns, 2.5 microns and 10.0 microns, and 10.0 microns and larger, or other particle size ranges of interest. The particle detector may include one or more of a bulk acoustic wave (BAW) resonator, a thin-film bulk acoustic wave resonator (FBAR), a solidly mounted resonator (SMR), a quartz crystal microbalance (QCM), a wall-mounted particle detector, a time-of-flight detector, a resonant sensor, a capacitive sensor, an infrared sensor, an optical sensor, a UV sensor, and a particle mass detector. An effective mass of the particles collected on the surface of the particle detector may be determined. An aerosol mass concentration estimate of the particles within the selected particle size range may be generated and provided to a requesting entity.

In some embodiments, the invention may be a system for analyzing particles that includes an inlet, a particle concentrator fluidically coupled to the inlet, and a particle discriminator fluidically coupled to the particle concentrator. The particle discriminator includes an air channel for containing an air stream. The air channel may extend from the inlet through the particle concentrator and through the particle discriminator.

A controller may be electrically coupled to the particle concentrator and to the particle discriminator and configured to allow concentrating particles in an interior region of the air stream and deflecting the concentrated particles in the air stream with a generated thermal gradient. Smaller particles in the air stream may be selectively deflected away from the interior region and towards a periphery of the air stream at a different rate than larger particles in the air stream. The controller may be further configured to allow controlling the generated thermal gradient to deflect particles in a selected particle size range onto a surface of a particle detector, controlling an airstream velocity of the air stream in the air channel, collecting deflected particles within a selected particle size range on a surface of a particle detector, determining an effective mass of the particles collected on the surface of the particle detector, generating an aerosol mass concentration estimate of the particles within the selected particle size range, and providing the aerosol mass concentration estimate.

In some embodiments, the invention may be a non-transitory computer-readable medium storing computer-readable program code to be executed by at least one processor for analyzing particles in an air stream includes instructions configured to cause concentrating particles in an interior region of the air stream and deflecting the concentrated particles in the air stream with a generated thermal gradient. Smaller particles in the air stream may be selectively deflected away from the interior region and towards a periphery of the air stream at a different rate than larger particles in the air stream. The instructions may further cause controlling the generated thermal gradient to deflect particles in a selected particle size range onto a surface of a particle detector, controlling an airstream velocity of the air stream in the air channel, collecting particles within a selected particle size range on a surface of the particle detector, determining an effective mass of the particles collected on the surface of the particle detector, generating an aerosol mass concentration estimate of the particles within the selected particle size range, and providing the aerosol mass concentration estimate.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1 shows a simplified block diagram of a system for analyzing particles in an air stream.

FIG. 2 illustrates a method of analyzing particles traversing a system for analyzing particles in an air stream.

FIG. 3 illustrates the elements and operation of a thermophoretic particle concentrator.

FIG. 4 illustrates the elements and operation of a thermophoretic particle discriminator.

FIG. 5 illustrates a method of fractionating and discriminating concentrated particles in an air stream.

FIG. 6 shows a plot of particle position across an air channel versus distance along the air channel having a thermophoretic particle concentrator and a thermophoretic particle discriminator.

FIG. 7 shows a block diagram of a system for analyzing particles in an air stream.

FIG. 8 depicts an exploded view of a system for analyzing particles in an air stream.

FIGS. 9A-9I illustrate top and cross-sectional views of various thin-film heater elements for use in systems for analyzing particles.

FIGS. 10A-10C illustrate perspective and cross-sectional views of a resonant-based particle detector.

FIGS. 11A-11B illustrate the operation of a system for analyzing particles in an air stream.

FIGS. 12A-12B illustrate a top view and a side view of a system for analyzing particles in an air stream.

FIGS. 13A-13B illustrate a perspective view and a side view of a system for analyzing particles.

FIGS. 14A-14D illustrate top and side views of a system with a rectangular air channel for analyzing particles in an air stream and operation thereof.

FIGS. 15A-15D illustrate top and side views of a system with an expanding air channel for analyzing particles in an air stream and operation thereof.

FIG. 16 illustrates a top view of a system for analyzing particles in an air stream including a centrifugal particle separator stage.

FIGS. 17A-17B illustrate top and side views of a system for analyzing particles with a widening air channel and a narrowing channel height.

FIGS. 18A-18B illustrate top and side views of a thermophoretic particle detection system for analyzing particles including a pair of multi-tapped heater elements extending through the particle concentrator and the particle discriminator.

FIG. 19 illustrates a block diagram of a system for analyzing particles in an air stream.

FIG. 20 shows a block diagram of a method for analyzing particles in an air stream.

FIG. 21 shows a block diagram of a method for analyzing particles including the generation of an aerosol mass concentration estimate.

DETAILED DESCRIPTION OF THE INVENTION

The techniques, methods, devices, and systems disclosed herein may result in smaller, simpler and lower cost airborne particle detection and monitoring devices that allow mass-market use in homes, buildings, workplace environments, industrial facilities, indoor and outdoor environments, and personal air-quality monitors. Improved airborne particle detection systems and methods may be used in a variety of devices including cellular phones, smartphones, laptop and tablet computers, thermostats, voice-activated tabletop monitors, wearable devices such as watches and personal health monitors, air monitors for green buildings and home-automation systems, vehicle cabin monitoring, smoke detectors and protective devices such as face masks and eyeglasses, among other applications.

Improved air particle monitoring devices can be facilitated by systems and methods configured to use thermophoretic forces. Such systems and methods can produce various effects useful for such improved devices by employing suitable thermal gradients. These effects may include concentrating and focusing particulate material, fractionating particulate material according to size, and directing various sizes of particulate material onto one or more suitable particle sensors such as resonant-based MEMS sensors or other devices in a controlled manner.

Thermophoretic force generally refers to the force that may be exerted on small particles such as micron and sub-micron sized particles that are suspended in a gas or fluid media in the presence of thermal gradients. Absent thermal gradients (also referred to as “temperature gradients” or “heat gradients”), suspended particles experience normal random Brownian motion. In the presence of thermal gradients, more energetic molecules of the gas or fluid media may impact one side of the particle relative to the other side of the particle, producing a net force on the particle that varies as a function of the particle diameter, temperature gradient, gas pressure, particle temperature and other variables such as the thermal conductivity and heat capacity of the particle. This thermophoretic force can, in turn, impart a thermophoretic velocity to such particles that varies as a function of the thermal gradient, gas viscosity, gas density and the size and composition of the particles. The thermophoretic force may be used to concentrate particles in an interior region of an air stream and to selectively deflect the particles towards suitable particle detectors for detection and analysis.

Airborne particle detection may be accomplished with a thermophoretic particle discriminator in combination with a particle concentrator. Particles in an interior region of an air stream may be deflected by thermophoretic forces generated from thermal gradients in the air stream. Smaller particles in the air stream may be selectively deflected away from the interior region of the air stream and towards a periphery of the air stream at a higher rate than larger particles, allowing differentiation of the airborne particles when collected by one or more particle detectors. Controlling the thermal gradients in the sample air stream and the airstream velocity in an air channel allows particles in a particular size range to be selectively deflected by the thermophoretic particle discriminator. Particles in a selected particle size range may be deflected, collected, detected and analyzed by one or more particle detectors such as resonant-based particle detectors.

While the embodiments disclosed herein generally refer to systems and methods for analyzing particles in an air stream, “air”, although encompassing normal earth atmospheric air, can be any type of gas or fluid traversing the air channel. Particles in the air stream generally refer to micron or sub-micron sized particles with a plurality of particle sizes and composition that are suspended in the air stream and are generally distinct from the smaller gas molecules or atoms comprising the carrier gas. A micron (also referred to as “μm”) is a unit of length equal to one micrometer or one-millionth of a meter.

Similarly numbered elements in the various figures below apply to similar elements. While the figures are intended to be illustrative, dimensions and features of the various elements shown in the figures are not always drawn to scale for clarity.

FIG. 1 shows a simplified block diagram of a system 100 for analyzing particles in an air stream. System 100 includes an inlet 110, a particle concentrator 120 and a particle discriminator 130. A set of data and control signals 140 may be used for communicating, sending and receiving data, and controlling system 100. Inlet air stream 112 may include particulate matter that may be concentrated by particle concentrator 120 and then deflected, collected, detected and analyzed by particle discriminator 130 and associated analytical components. Outlet air stream 118 may include air drawn from the inlet 110 absent particles collected by particle discriminator 130.

In some implementations, system 100 may be wired or wirelessly coupled to a cell phone, smartphone, laptop, or other computerized devices, to enable one or more processors within the system 100 or computerized device to process the data from system 100 and produce temporal and spatial (if multiple such systems are used) measurements of particulate matter content. In some implementations, system 100 may be communicatively coupled to one or more processors in a data center or a cloud computing environment to perform data processing of the particulate matter data and to provide results of particulate matter data procured from system 100.

FIG. 2 illustrates a method of analyzing particles 114 traversing a system 200 for analyzing particles in an air stream. Particles 114 in the inlet air stream 112 passing through the inlet 110 are drawn through an air channel 102 (also referred to as a “flow channel”) that is encompassed by one or more channel walls 104. Without any focusing or concentration, particles 114 generally follow an air stream 106 (also referred to as a “flow stream”) in the air channel 102 along one or more streamlines 108. Particles deflected by applied forces such as thermophoretic force or gravitational force may be deflected away from a particular streamline 108 in the direction of the applied force.

Airborne particles 114 may have different sizes and shapes and comprise different materials or aggregates of various materials. Various types of airborne particles 114 at the inlet air stream 112 are depicted and labeled 1 through 8, indicating larger spherical particles 1 and 5, smaller spherical particles 2 and 6, fibrous particles 3 and 7, and fractured particles 4 and 8. As these particles 114 traverse the air channel 102, thermophoretic forces from heater elements 122 a, 122 b (also referred to as “heating elements” or “focusing heaters”) in the particle concentrator 120 may force particles 114 away from a periphery of the air channel 102 near the channel walls 104 and towards an interior region 220 of the air channel 102 that may be at or near the geometrical center of the air channel 102. Thermophoretic particle concentrator heater elements 122 a, 122 b may be used to focus incoming particles 114 into a tighter beam to facilitate analysis. Particles 114 concentrated in an interior region 220 of air channel 102 may progress towards the particle discriminator 130 along one or more streamlines 108.

Particle discriminator 130 may include one or more heater elements 132 (also referred to as a “precipitation heater” or a “deflection heater”) to deflect and collect particles on a wall 104 or particle detector 134 opposite the heater element 132. Particles 114 may be deflected by thermal gradients generated by the thermophoretic particle discriminator heater element 132 and directed towards a particle detector 134 near the wall 104 where particles in a selected particle size range may be collected on a surface 136 of the particle detector 134. The collected particles 116 may cause a shift in a resonant frequency of the particle detector 134, which may be calibrated to determine the amount of mass collected on the surface 136. Fractionation, collection, detection and analysis of particles 114 in a particular size range depend in part on size-dependent and composition-dependent thermophoretic forces and an initial well-collimated and pre-focused stream of incoming particles 114. Uncollected particles may continue down the air channel 102 along one or more streamlines 108 and exit via the outlet air stream 118.

FIG. 3 illustrates some of the elements and operation of a thermophoretic particle concentrator 120. Thermophoretic particle concentrator 120 may include at least one pair of thermophoretic particle concentrator heater elements 122 a, 122 b positioned near a periphery of an air channel 102 within the particle concentrator 120. Particle concentrator 120 may include an air channel 102 with a first open end for inlet air stream 112 and a second open end for outlet air stream 118 that allows particles 114 and air stream 106 to traverse the air channel 102. The air channel 102 may be enclosed by one or more channel walls 104 extending from at least the first open end to the second open end. Two or more heater elements 122 a, 122 b may be positioned between the first open end and the second open end. The heater elements 122 a, 122 b may be positioned near a periphery of the air channel 102 and cooperatively configured to thermophoretically force particles 114 in the air stream 106 away from the periphery and towards an interior region 320 of the air channel 102.

In some embodiments, a position-dependent heat profile may be generated along the length of the air channel 102 to drive particles 114 towards the center of the air channel 102, while otherwise allowing the air stream 106 to remain unperturbed. Particles 114 in the air stream 106 may be thermophoretically forced towards the interior region 320 of the air channel when the heater elements 122 a, 122 b are heated and thermal gradients emanating from heater elements 122 a, 122 b are generated. Isothermal lines 324 a, 324 b show lines of constant temperature within the air stream 106. As power applied to heater elements 122 a, 122 b changes and as the velocity of air stream 106 is adjusted, the position and the shape of isothermal lines 324 a, 324 b may change. Thermophoretic forces 326 a, 326 b may be generated and act on particles 114 as particles 114 in the air stream 106 traverse the air channel 102. Thermophoretic forces 326 a, 326 b increase as the thermal gradients in the air channel 102 increase and act on particles 114 in the direction of most rapid thermal decrease, that is, in a direction perpendicular to the isothermal lines 324 a, 324 b and with a magnitude proportional to the gradient of the temperature in the air stream 106. When acted upon by thermophoretic forces 326 a, 326 b generated by the thermal gradients in the air stream 106, particles 114 may be forced away from the periphery and towards an interior region 320 of the air channel 102. The particles 114 may be deflected across streamlines 108 towards the center of the air channel 102, increasing the concentration of particles 114 in the interior region 320 of the air channel 102. In some implementations, the temperatures of the heater elements 122 a, 122 b may be varied to control the position of the concentrated particles 114 within the interior region 320 as the particles 114 continue downstream in the air channel 102.

While the interior region 320 of the particle concentrator 120 (and of the particle discriminator 130) is generally centered on the geometric center of the air channel 102 and includes portions of the air channel 102 in the vicinity of the geometric center, in some implementations the interior region 320 may be centered about an axis that is offset from the centerline of the air channel 102. Dimensions of the interior region are generally on the order of the width and/or length of the active sensor area of the particle detector 134, which may be 200 microns or less. As particle fractionation and collection improves with a tighter distribution of particles in the interior region of the air stream 106, device performance improves with a tighter particle distribution. In some implementations, the interior region may be defined as the spatial volume where a simple majority of airborne particles 114 in the air stream 106 are concentrated. In some implementations, the interior region may be defined as a percentage of the channel volume, such as 1%, 2%, 5%, 25% or 50% of the channel volume. In some implementations, the interior region may include the geometric center of the air channel and a percentage of the area about the geometric center, such as 1%, 2%, 5%, 25% or 50% of the cross-sectional area at a point along the centerline of the air channel.

FIG. 4 illustrates the elements and operation of a thermophoretic particle discriminator 130. The particle discriminator 130, sometimes referred to as a deposition chamber or a settling chamber, includes an air channel 102 having one or more channel walls 104 that contain an air stream 106. The air channel 102 in the particle discriminator 130 may extend from the inlet 110 through a particle concentrator 120 and through the particle discriminator 130. The particle discriminator 130 may be fluidically coupled to the particle concentrator 120 and to the inlet 110. Particles 114 in the air channel 102 may be concentrated in an interior region of the air stream 106 within the particle concentrator 120 and then passed via the fluidically coupled air channel 102 into the particle discriminator 130.

The particle discriminator 130 may include at least one thermophoretic particle discriminator heater element 132. Heater element 132 may be configured to deflect particles 114 in an interior region of the air stream 106 towards a peripheral wall 104 of an air channel 102 that encompasses the air stream 106. A thermal gradient in the air channel 102 generated by the heater element 132 may thermophoretically force particles 114 towards the peripheral wall 104 in a direction perpendicular to the air stream 106. Isothermal lines 434 a, 434 b show lines of constant temperature. The position and shape of isothermal lines 434 a, 434 b may change as the power applied to heater element 132 changes and as the velocity of air stream 106 is adjusted.

As particles 114 enter particle discriminator 130, the thermophoretic force generated by one or more heater elements 132 in the particle discriminator 130 may force particles 114 towards a periphery of the air stream 106 near one of the channel walls 104 of the particle discriminator 130. Thermophoretic forces 436 a, 436 b may be generated and act on particles 114 as particles 114 in the air stream 106 traverse the air channel 102. Thermophoretic forces 436 a, 436 b increase as the thermal gradient in the air channel 102 increases and act on particles 114 in the direction of greatest decrease in temperature with respect to position. When acted upon by thermophoretic forces 436 a, 436 b generated by the thermal gradients in the air stream 106, particles 114 are forced away from the interior region of the air channel 102 and towards a periphery wall 104.

The particles 114 may be deflected away from the interior region of the air channel 102 and towards a particle detector 134 positioned on the periphery wall 104 of the air channel 102. The particle detector 134 may be configured to collect particles 114 deflected from the interior region of the air stream 106. Deflected particles 114 may be collected on a surface 136 of a particle detector 134 where the collected particles 116 may be detected and analyzed. Smaller particles in the air stream 106 may be selectively deflected away from the interior region and towards a periphery of the air stream 106 at a different rate than larger particles in the air stream. Particles may be subject to area-dependent viscous and drag forces and to gravitational forces that are density and volume dependent. Heavier particles, for example, may be selectively deflected by gravitational forces at a higher rate than lighter particles of similar size.

Power applied to the heater element 132 of the particle discriminator 130 may be controlled to generate and control thermal gradients in the air channel 102 to deflect particles 114 in a selected particle size range onto a surface 136 of the particle detector 134. The selected particle size range may include a particle size range between about 0.01 microns and 0.1 microns, 0.01 microns and 0.3 microns, 0.1 microns and 1.0 microns, 1.0 microns and 2.5 microns, 2.5 microns and 10.0 microns, and 10.0 microns and larger, or other particle size ranges of interest. Particles 114 not collected by the particle discriminator 130 may continue downstream along one or more streamlines 108 and through the outlet air stream 118. In some implementations, power applied to heater element 132 may be dithered, modulated or otherwise varied to more evenly spread the distribution of collected particles 116 on the surface 136 of the particle detector 134. In some implementations, the power applied to heater element 132 may be varied sequentially in time to collect and analyze particles of a first size during a first time period, then collect and analyze particles of a second size during a second time period, and so forth.

FIG. 5 illustrates a method of fractionating and discriminating concentrated particles 114 in an air stream 106. A cross-sectional view of a particle discriminator 130 is shown with an air channel 102 and channel walls 104 encompassing the air channel 102 and the air stream 106. Particles 114 from an inlet air stream 112 that are concentrated in an interior region of the air stream 106 may be deflected towards a peripheral wall 104 of the air channel 102 with one or more heater elements 132 in the particle discriminator 130. The particles may be deflected with a thermal gradient generated by the heater element 132, with smaller particles 552, 554 in the air stream 106 deflected away from the interior region and towards a periphery of the air stream 106 at a higher rate than larger particles 556, 558 in the air stream. The amount of transverse displacement of the various particles may change in an amount that varies roughly inversely with the size of the airborne particles. That is, smaller sized particles are generally deflected more than larger sized particles. The trajectory of smaller particles under the influence of thermophoretic forces is more readily altered compared to larger particles under the same influences, allowing localized particle detectors to distinguish between different particle sizes. The rate of deflection may also be a function of mass, thermal conductivity, surface area, and other properties of the deflected particles. For example, denser particles of similar size may be selectively deflected at a different rate than less dense particles.

A plurality of particle detectors 134 a, 134 b, 134 c may be positioned on a channel wall 104 of the particle discriminator 130 to allow collection and detection of particles within one or more particle size ranges. The lighter (smaller) particles may be collected by the first particle detector 134 a and the heavier (larger) particles may be collected by the second or third particle detectors 134 b, 134 c, allowing the particle discriminator 130 to distinguish between different particle sizes. The physical mechanism for such size fractionation and discrimination assumes some form of pre-focusing or concentration of the particulate matter stream within the air channel 102 to prevent a given particle detector 134 a, 134 b, 134 c from collecting a mixture of different particle sizes from different heights or locations in the sample air stream 106. In the absence of active measures to concentrate the particles 114 into a beam, the particles 114 may be distributed throughout the entire vertical profile of air channel 102. Thus large particles 114 positioned near the bottom of the air channel 102 may be deflected onto the first particle detector 134 a while smaller particles 114 near the top of the air channel 102 may be deflected onto the second particle detector 134 b, interfering with the ability of the particle discriminator 130 to distinguish between different particle sizes or other particle properties.

Power to the heater element 132 may be controlled to allow collection of the deflected particles in a particular particle size range onto a surface of one of the particle detectors 134 a, 134 b, 134 c. As illustrated in FIG. 5, smaller particles 552′ may be collected on particle detector 134 a; somewhat larger particles 554′ may be collected on particle detector 134 b; larger particles 556′ may be collected on particle detector 134 c; and the largest particles 558′ may remain uncollected and continue along the air stream 106 through the outlet air stream 118, effectively generating a cutoff point for particle collection.

FIG. 6 shows a plot 600 of particle position across an air channel versus distance along the air channel having a thermophoretic particle concentrator 120 and a thermophoretic particle discriminator 130. Particles in the air stream initially distributed uniformly across the channel height enter the particle concentrator 120 and are forced towards the interior region of the air stream by heater elements 122 a, 122 b as previously described. The concentrated particles traverse the air channel towards a particle discriminator 130. The particle discriminator 130 is positioned in a downstream direction of the air stream with respect to the particle concentrator 120.

Under normal atmospheric pressure, smaller particles, such as particles under about 2.5 microns in size, are minimally affected by gravity. These particles tend to move through the air channel with minimal deflection due to gravity. Absent any other forces, these particles follow almost the same path as the surrounding air in the air channel. To detect and measure suspended aerosol particles, a precipitating thermophoretic force may be applied to the particles to deflect the particle's trajectory enough so that the particle may be propelled towards and collected on the surface of one or more particle detectors 134 a, 134 b, 134 c, 134 d.

The particle discriminator 130 may have at least one heater element 132 and an array of particle detectors 134 a, 134 b, 134 c, 134 d disposed on a wall of the air channel opposite the heater element 132 that is configured to collect deflected and fractionated particles. Lighter and smaller particles 632 may be deflected at a higher rate and collected by particle detector 134 a. Heavier and larger particles 634 may be deflected at a lower rate and collected by particle detector 134 d. Still heavier and larger particles 636 may remain uncollected and may be passed along the air channel where they may be deflected downwards by gravitational forces acting on the particles.

Particles smaller than a particular cutoff size, such as 2.5 microns in diameter, may be selectively collected and analyzed by the particle discriminator 130 and particles larger than the cutoff size may continue past the particle discriminator 130. Heavier and larger particles 636 above the cutoff point that are near the periphery of the air channel may experience a lower local velocity of air than that of particles near the center of the air channel, allowing gravitational forces more time to act on the heavier particles. The effect of gravity and the orientation of the particle discriminator 130 can affect the cutoff size.

Because the thermophoretic force can be made much greater than the force of gravity, at least for particles sized less than about 10 microns, the particle sensors may be configured on nearly any surface of the air channel including (relative to the force of gravity) the floor, the ceiling, or the sides of the air channel. Although in this disclosure floor and ceiling mounted particle detectors are mainly discussed, this is not intended to be limiting. Given the comparatively large impact that precipitation heaters can have on particle trajectories, particle sensors can also be mounted on the sides of an air channel (relative to the force of gravity) or upside down as desired.

In some implementations, a thermophoretic particle detection system may be configured with one or more additional stages of particle concentrators 120 and particle discriminators 130 positioned downstream of a first stage. Thermophoretic forces act on smaller particles and deflect the smaller particles at a faster rate than larger particles in the air stream. The first stage allows concentration of particles in the air stream and collection of particles in a first particle size range while passing particles outside of the first range. A second stage allows re-concentrating and re-focusing of particles remaining in the air stream and subsequent collection of particles in a second range with a larger particle size range than the first stage. Additional stages with pairs of particle concentrators 120 and particle discriminators 130 may be added. Each stage may include one or more focusing heaters in the particle concentrator 120 and one or more deflection heaters and particle detectors in the particle discriminator 130 to redirect larger particles towards the center of the air channel that may be re-concentrated and re-deflected for additional collection and analysis. In some implementations, multiple stages of particle concentrators and discriminators allow further separation of resonant-based particle detectors resulting in improved acoustic isolation and less mechanical coupling between detectors for improved sensitivity.

FIG. 7 shows a block diagram of a system 700 for analyzing particles in an air stream. System 700 includes an inlet 110, a particle concentrator 120 fluidically coupled to the inlet 110, and a particle discriminator 130 fluidically coupled to the particle concentrator 120. The inlet 110, particle concentrator 120 and particle discriminator 130 include an air channel 102 extending through the inlet 110, particle concentrator 120 and particle discriminator 130 for containing an air stream 106. The air channel 102 includes one or more channel walls 104 for containing the air stream 106. One or more heater elements 122 a, 122 b may be positioned on opposing sides of the air channel 102 within the thermophoretic particle concentrator 120. One or more heater elements 132 may be positioned on a channel wall 104 of air channel 102 within the particle discriminator 130. One or more particle detectors 134 may be positioned on a wall 104 of the particle discriminator 130 opposite the heater elements 132 to collect and detect particles. The particle detectors 134 may include one or more piezoelectric layers 734 with electrode layers 732, 736 on each side of the piezoelectric layer 734.

System 700 may include one or more controllers 150. Controller 150 may include one or more processors configured to allow concentrating particles 114 in an interior region of the air stream 106 within the particle concentrator 120 and deflecting the concentrated particles 114 in the air stream 106 within the particle discriminator 130 with generated and controlled thermal gradients in the air channel 102. Controller 150 may include various electronic circuits, passive devices, metal traces, electrical interconnects and wires for sending signals to and receiving signals from heater elements 122 a, 122 b, heater element 132 and particle detector 134. Electrical power and ground connections for controller 150 may also be provided.

Controller 150 may include circuitry to operate the particle detector 134 in a resonant mode and to detect changes in the resonant frequency. The circuitry may include signal amplifiers and preamplifiers, signal conditioning circuitry such as filters, mixers, local oscillators, demodulators, phase-lock loops, counters, A-D (analog to digital) convertors, and divide-by-n circuits, and control circuitry to determine the frequency shifts associated with mass loading from collected particles on the surface of the particle detector 134. The controller 150 may include processing circuitry to process data from the particle detector 134 and to analyze properties of the collected particles.

Smaller particles 114 in the air stream 106 may be selectively deflected away from the interior region of the air channel 102 and towards a periphery of the air stream 106 at a higher rate than larger particles 114 in the air stream 106. The controller 150 may be configured to allow controlling the generated thermal gradient to deflect the particles in a selected particle size range onto a surface 136 of the particle detector 134. The controller 150 may be configured to draw air and to control an airstream velocity of the air stream 106 in the air channel 102. The controller 150 may be configured to allow collecting particles 114 within a selected particle size range on the surface 136 of particle detector 134. The controller 150 may be configured to determine an effective mass of the particles 114 collected on the surface 136 of the particle detector 134. The controller 150 may be configured to generate an aerosol mass concentration estimate of the particles 114 within the selected particle size range and provide or send the generated aerosol mass concentration estimate via the data and control signals 140 to another location. The controller may be configured to correct or compensate for temperature, relative humidity, ambient pressure, and other factors. The controller may be configured to operate in these manners using non-transitory computer-readable medium storing computer-readable program code to be executed by at least one processor associated with the controller for analyzing particles in an air stream through the use of associated program code including associated program instructions.

FIG. 8 depicts an exploded view of a system 800 for analyzing particles in an air stream 106. System 800 includes an inlet 110 having an inlet port 812 with an open end 814 for an inlet air stream 112. System 800 may include an outlet port 818 with an open end 816 for an outlet air stream 118. An air channel 102 may encompass the air stream 106 and extend from the open end 814 to the open end 816. The size and shape of the open ends 814 and 816 may vary depending on the device and application. For example, circular open ends 814 and 816 may have a diameter between about 30 microns and about 50 millimeters. Rectangular open ends 814 and 816 may have a width between about 30 microns and about 50 millimeters and a height between about 30 microns and about 50 millimeters.

The thermophoretic particle concentrator 120 may have two heater elements 122 a, 122 b positioned on opposite sides of the air channel 102. A thermophoretic particle discriminator 130 may have one or more heater elements 132 positioned on one side of the air channel 102 and a particle detector 134 positioned on the opposite side of the air channel 102. In the implementation shown in FIG. 8, the air channel 102 is circular and the heater elements 122 a, 122 b and 132 are positioned along a circumference of the channel wall in a direction substantially perpendicular to the air stream 106 flowing in the air channel 102. Particles in the air stream 106 may be thermophoretically forced towards an interior region 820 of the air channel 102 when the heater elements 122 a, 122 b are heated and thermal gradients emanating from the heater elements 122 a, 122 b are generated. Heater elements 122 a, 122 b and heater element 132 may include one or more thin-film heater elements, resistive films, resistive segments, heater wires, or other heater types. For economic and packaging reasons, the same heater type may be used in either or both the particle concentrator 120 and the particle discriminator 130, although each heater will generally operate at a different temperature depending on their use as a focusing heater or a precipitation heater. The operating temperature may vary depending in part on the shape and placement of the heater elements, the resistivity of the heater elements, and the applied power. Operating temperatures for heater elements in the thermophoretic particle concentrator 120 are typically between about 20 degrees centigrade and 50 degrees centigrade above ambient temperature. Operating temperatures for heater elements in the thermophoretic particle discriminator 130 are generally higher and are typically between about 50 degrees centigrade and 200 degrees centigrade above ambient temperature for effective control of particle movement. The temperature of the heater elements 122 a, 122 b and 132 and the thermal gradients generated therefrom may be controlled by controlling the electrical power applied to each of the heater elements, such as by controlling the amount of electrical current passed through the heater elements or by controlling the voltage applied across the terminals of the heater elements.

One or more banded heater elements 822 a, 822 b may be positioned on or around portions of the inlet port 812. The banded heater elements 822 a, 822 b allow circular or rectangular inlet ports 812 to be surrounded with heater elements that extend around the entire inlet wall 104. The banded heater elements 822 a, 822 b may be configured with heater segments disposed on opposite sides of the air channel 102 that encompasses the air stream 106. The Power applied to inlet heater elements 822 a, 822 b may generate thermophoretic forces acting on particles in the incident air stream 106, forcing the particles away from the walls 104 of the air channel 102 towards an interior region 820 of the air stream 106 and beginning the particle concentration process. Further concentration of particles in the air stream 106 may occur in the thermophoretic particle concentrator 120 downstream of the inlet air stream 112. Temperatures generated by the banded heater elements 822 a, 822 b may be as low as a few degrees above ambient temperature to deter particles from collecting on surfaces of the inlet port 812. The banded heater elements 822 a, 822 b may be configured to control or limit the level of moisture or humidity in the air channel 102 during use.

Data and control signals 140 may be communicated to and from system 800 with one or more electrical connectors and signal lines coupled to system 800. The air channel 102 includes one or more channel walls 104. The sides of the air channel 102 will normally be surrounded by walls 104, except at the open ends for the inlet air stream 112 and the outlet air stream 118. At least one particle detector 134 may be positioned along the wall 104 and configured so that the airborne particles, after being propelled transversely by the precipitation heat gradient produced by the precipitation heater element 132, may be detected by the particle detector 134.

While thermophoretic particle discriminators 130 are generally used as exemplary embodiments in the various descriptions contained herein, other detection devices and methods such as particle sensors that operate by laser light scattering are also possible and are not disclaimed by this disclosure. The embodiments described herein may operate with many different types of particle sensors. MEMS-based particle sensors and in particular an FBAR sensor or an addressable array of FBAR sensors are presented as a particular type of particle detector that may be used.

Air or other carrier gas may be drawn through the air channel 102 with an air movement device (not shown) generally positioned downstream of the outlet air stream 118 to generate the air stream 106. The air movement device may include a pump, blower, fan, turbine, motorized air intake device, bellows pump, membrane pump, peristaltic pump, piston pump, positive-displacement pump, rotary vane pump, Venturi device, airflow management device, or other air drawing means for moving or drawing air through the air channel 102. In some implementations, the air velocity of the inlet air stream 112 in the system 800 may be adequate without requiring active airflow generation by using a passive airflow mechanism such as an ambient air flow, an ambient pressure drop across the length of the air channel, or a convective heat process.

Particulate filters (not shown) and protective screens may be used upstream of the particle concentrator 120 to filter out particularly large particles and to protect the air channel 102 from accumulating undesirable debris. In some implementations, a size-selective particle filter or a size-selective input device may be included as part of the inlet 110 or placed upstream of the inlet 110. In some implementations, the walls 104 of the air channel 102 may be mechanically supported and mounted in a way that provides for improved thermal isolation. In some implementations, the air channel 102 may be suspended in an aerogel that provides good mechanical robustness and good thermal isolation.

FIGS. 9A-9I illustrate top and cross-sectional views of various thin-film heater elements for use in systems for analyzing particles. Thin-film heater element 900 shown in FIG. 9A includes a thin heater layer 910 such as a patterned layer of nickel, chrome-nickel or platinum. Electrical bond pads 940 and 950 allow electrical connections to the heater layer 910 via heater contact regions 944 and 954, respectively. One or more electrical traces 946 may be used to facilitate electrical connections between bond pad 940 and contact region 944. Similarly, one or more electrical traces 956 may be used to facilitate electrical connections between bond pad 950 and contact region 954. The illustrative cross-sectional view shown in FIG. 9B taken through dashed lines AA′ in FIG. 9A shows heater layer 910 positioned between two insulating layers 912 and 916 such as layers of silicon dioxide or silicon nitride. The heater layer 910 may be positioned above a cavity region 918 defined in a heater substrate 920 to reduce power loss through the heater substrate 920. Bond wires 942 and 952, or other connective wiring, may be used to make connections to bond pads 940 and 950, respectively.

FIG. 9C shows a thin-film heater element 900 with heater layer 910 patterned in a serpentine manner having various heater segments 922 a-922 f serially connected to each other and electrically connected to electrical bond pads 940 and 950. Alternative implementations of thin-film heater elements include metal foil formed into electrically connected serpentine heater segments on polyimide film backing such as Kapton tape with patterned electrodes, or other microfabricated heater elements such as polysilicon heater elements formed on fused quartz substrates. In some implementations, other sources of heat such as high-resistivity wire, heat pipes, radiant heating or inductive heating may be used to generate the thermal gradients.

FIG. 9D illustrates a cross-sectional view of a thermally isolated wall-mounted thin-film heater element 900 with a polymeric barrier layer 904 that may serve as a channel wall of an air channel. The wall-mounted thin-film heater element 900 in FIG. 9D presents no structural features in the air channel except for the relatively smooth outer surface of the polymeric barrier layer 904, minimizing the level of any airflow disruptions in the air stream. A thin heater layer 910 may be formed separately on a plastic heater substrate 920 and laminated or otherwise attached to the barrier layer 904 with an adhesive layer 906 such as a UV-curable adhesive or epoxy. The heater layer 910 may be electrically connected to bond pads 940 and 950 with one or more electrical traces 946 and 956, respectively. The bond pads 940 and 950 may be attached with anisotropic conductive film (ACF) 980 to electrical interconnects formed on one or more interconnect layers 962, 964 through one or more plated flex via holes 966 and dielectric layers 968 included in a flexible printed circuit board 960 (also referred to as a “flex”). The construction shown with a cutout region in one of the flex layers 970 generates a cavity region 918 between the heater layer 910 and the underlying flex layer 972 that allows a higher level of thermal isolation and lower operating power to achieve the same operating temperature. Additional cavity regions (not shown) may be formed in underlying flex layers 972, 974 of the flexible printed circuit board 960 to achieve additional thermal isolation. Thermal isolation of the thin-film heater layer 910 may result in improved temperature control, less temperature variation, and lower operating power. The cavity region 918 may be filled with an aerogel or other thermally insulating material to provide mechanical strength in addition to thermal isolation.

FIG. 9E illustrates a top view of a multi-tapped thin-film heater element 900. The multi-tapped thin-film heater element 900 in FIG. 9E may be attached to a polymeric barrier layer that in turn may serve as a channel wall of an air channel. The heater layer 910 may be disposed on a plastic heater substrate 920 and electrically connected to bond pads 940, 950 via the contact regions 944, 954 and electrical traces 946, 956, among others. Each heater segment 922 g through 922 r between two adjacent heater taps may be individually controlled by the voltages applied across each segment to allow control of a temperature profile in an adjacent air stream 106. Voltages between adjacent heater taps can step up or step down in voltage level as desired to control the power applied to the heater segment between the adjacent heater taps. Setting the electrical potential difference to zero across any two adjacent heater taps reduces the thermal generation between the two adjacent heater taps to zero, allowing temperature zone control and flow-dependent temperature distributions along the length of the multi-tapped heater element. Multi-tapped heater elements require fewer electrical connections compared to individually tapped heater elements and allow closer-spaced and continuous heater segments for improved temperature profile control. One or more pairs of multi-tapped heater elements may be formed on the heater substrate 920. The heater segments between any two heater taps may be formed in any one of a variety of shapes including straight segments, curved segments, angled segments, tapered segments, serpentine segments and segments with varying widths. One or more stub heater segments 9221, 922 r may be included on the substrate 920 with independent electrical access to allow additional control over the temperature profile and thermal gradients generated in the air stream 106.

FIG. 9F through FIG. 9I show top views of various thin-film heater elements 900 with thermally coupled heat spreaders. Heat spreaders are thermally conductive structures that heat up when nearby thermally coupled heater elements or heater segments are heated up. The heat spreaders may heat up to temperatures that are generally less than the temperature of the associated heater element, allowing improved control of the temperature distribution across the air channel 102 as an air stream 106 passes by the heater elements and heat spreaders. The heat spreaders may or may not carry current and are largely passive devices. While the heat spreaders may be mechanically and electrically connected to and in some implementations be formed from the same material as the heater elements, the heat spreaders may be fully passive devices that are electrically isolated from the heater elements yet close enough to extract thermal energy from the heater elements and redistribute the thermal energy throughout other portions of the air channel. The quantity and shape of the heat spreaders may vary from heater to heater or from segment to segment within the same air channel. For example, a pair of triangular heat spreaders 938 a, 938 b may be thermally coupled to heater segments 922 s, 922 t positioned near a channel wall 104 of an air channel 102 to selectively heat up air or other gas in the air stream 106 flowing through the air channel 102, as shown in FIG. 9F. An array of spike-shaped heat spreaders 938 c, 938 d, 938 e, 938 f among others may be thermally coupled to heater segments 922 u, 922 v, as shown in FIG. 9G. A thermally coupled heat spreader 938 h that extends across the air channel 102 to heater segments 922 w, 922 x may be tapered or otherwise contoured between the heater segments 922 w, 922 x, as shown in FIG. 9H. Heat spreader 938 i may extend between and overlap associated heater segments 922 y, 922 z, as shown in FIG. 9I. Heater taps 928 a through 928 p may provide electrical connectivity to each of the heater elements or heater segments shown in FIG. 9F through FIG. 9I. One or more passive metallic heat shunts (not shown) may be configured on one or more layers of a multi-layer flexible printed circuit board to serve as a thermal load and to alter the dynamic temperature response resulting in higher and more controlled thermal gradients in the air channel. One or more heat sinks (not shown) may be included to maintain a desired temperature such as an ambient temperature along one or more portions of the air channel.

Various heat spreaders, stub heaters, heat shunts, and heat sinks may be combined with one or more multi-tapped thin-film heater elements and control electronics to generate the desired thermal gradients in the air channel for focusing, concentrating, deflecting and collecting particles in the air stream. Thermal potential wells generated in the air stream with control of the thermal fields from the various heat spreaders, stub heaters, heat shunts, heat sinks, heater segments, and heater elements can effectively garner and capture particles in the air stream 106 for detection and analysis.

FIGS. 10A-10C illustrate perspective and cross-sectional views of a resonant-based particle detector 134. The resonant-based particle detector 134 may be an acoustic resonator device such as quartz crystal microbalance or a film bulk acoustic resonator having a surface exposed to air or gas-borne particles. Particles collected on the surface of the resonator may change the resonant frequency of the resonant device. The change in the resonant frequency due to the additional mass loading may be detected electronically. The resonant device may operate in a frequency range between a few megahertz and several gigahertz, with a detectable frequency shift on the order of a few Hertz that generally shifts downwards as mass is added.

The particle detector 134 may include one or more of a bulk acoustic wave (BAW) resonator, a thin-film bulk acoustic wave resonator (FBAR), a solidly mounted resonator (SMR), a quartz crystal microbalance (QCM), a wall-mounted particle detector, a time-of-flight detector, a resonant sensor, a capacitive sensor, an infrared sensor, an optical sensor, a UV sensor, or a particle mass detector. In some implementations, the particle detector may include a one-dimensional or two-dimensional array of such sensors, or more than one type of particle sensor. The particle detector may be positioned on or near a wall of an air channel 102 and may be arranged under or near a heater element 132 of a particle discriminator 130. In some implementations, particles in a selected particle size range may be deflected and collected on a surface 136 of the particle detector 134. The particle detector 134 may be used to determine an effective mass and other properties of the particles collected on the surface such as an aerosol mass concentration estimate.

In the implementation of FIG. 10A, a depiction of an FBAR-based particle detector 134 is shown including bond pads 1010 a, 1010 b, 1010 c disposed on a substrate 1020 with an FBAR 1030 suspended over a cavity 1038 and a portion of the collected particles 116 on a surface 136 of the FBAR 1030. Bond pads 1010 a, 1010 b, 1010 c may be used to make electrical connections such as signal and ground to the FBAR 1030. The cross-sectional view of the FBAR 1030 in FIG. 10B shows the collected particles 116 on the surface 136 of the FBAR 1030. The FBAR 1030 may include a piezoelectric layer stack having a piezoelectric layer 1034, an upper electrode 1036, and a lower electrode 1032 suspended over a cavity 1038 with the FBAR 1030 suspended partially over a cavity region 1038 formed in the substrate 1020. The cavity 1038 may be formed underneath the piezoelectric layer stack to improve the acoustic isolation and reduce energy loss to the substrate 1020. One or more dielectric layers 1022, 1024 such as a layer of silicon dioxide or silicon nitride may be used to provide electrical isolation for the bond pads 1010 a, 1010 b, 1010 c and various electrical traces 1046, 1056 positioned between the FBAR electrodes 1032, 1036 and the bond pads 1010 a, 1010 b, 1010 c. In some implementations, the electrodes 1032, 1036 and electrical traces 1046, 1056 may comprise one or more layers of aluminum or molybdenum.

FIG. 10C illustrates a cross-sectional view of an acoustically isolated wall-mounted particle detector 134 with a polymeric barrier layer 1004 that may serve as one of the channel walls of an air channel. The wall-mounted particle detector 134 presents no structural features in the air channel except for the relatively smooth outer surface of the polymeric barrier layer 1004, minimizing the level of any airflow disruptions in the air stream. The particle detector 134 may include an FBAR 1030 having a piezoelectric layer stack with a piezoelectric layer 1034, an upper electrode 1036, and a lower electrode 1032 suspended over a cavity region 1038 in the substrate 1020. One or more dielectric layers 1022 may be used to provide electrical isolation for the bond pads 1010 a, 1010 b and various electrical traces 1046, 1056 positioned between the FBAR electrodes 1032, 1036 and the bond pads 1010 a, 1010 b. The FBAR 1030 may be laminated or otherwise attached to the barrier layer 1004 with an adhesive layer 1006 such as a UV-curable adhesive or epoxy. The bond pads 1010 a and 1010 b may be attached with anisotropic conductive film (ACF) 1080 to electrical interconnects formed on one or more interconnect layers 1062, 1064 through one or more plated flex via holes 1066 and dielectric layers 1068 included in a flexible printed circuit board 1060. The construction is shown with a cutout region in two of the flex layers 1070 and 1072 generates a cavity region 1018 between the substrate 1020 and the underlying flex layer 1074 that allows a higher level of mechanical and acoustic isolation for the particle detector 134. Mechanical isolation of the particle detector 134 may result in improved sensitivity to added mass and less acoustic and mechanical coupling to other components.

Thermophoretic particle detection systems may include one or more flex-based wall-mounted heater elements such as that shown in FIG. 9D and one or more flex-based wall-mounted particle detectors 134 such as that shown in FIG. 10C. Flex-based air channels may be formed by combining the flex-based heater elements and the flex-based particle detectors with suitable flex-based sidewalls to form a rectangular air channel with continuous, smooth walls and surfaces through the inlet, particle concentrator and particle discriminator. For example, one or more layers of polyimide may be combined with the multi-layer flex assemblies and be used as the polymeric barrier layer 904 and 1004 and as the side walls of the air channel for a compact, low-profile airborne particle detector.

FIGS. 11A-11B illustrate the operation of a system 1100 for analyzing particles in an air stream 106. FIG. 11A shows a cross-sectional view of a system 1100 having an inlet 110, a thermophoretic particle concentrator 120 and a thermophoretic particle discriminator 130. An inlet air stream 112 entering an air channel 102 between walls 104 at various local velocities 1112 forms a local velocity profile 1114 that can vary across the width, height and length of the air channel 102 yet generally has a higher local velocity near the center of the air channel 102 that diminishes to nearly zero near the walls 104 of the air channel 102.

When heater elements 122 a, 122 b on opposite sides of the particle concentrator 120 are heated, thermal gradients are generated throughout the air channel 102, which in turn generate thermophoretic forces 1126 a, 1126 b that are perpendicular to isothermal lines 1124 a, 1124 b and point generally in the direction of the steepest negative thermal gradient. Particles in the air stream 106 may be directed away from a periphery of the air channel 102 in the particle concentrator 120 and towards an interior region of the air channel 102.

When heater elements 132 on one side of the particle discriminator 130 are heated, thermal gradients are generated throughout the air channel 102, which in turn generate thermophoretic forces 1136 a, 1136 b that are perpendicular to isothermal lines 1134 a, 1134 b and point in the direction of the steepest negative thermal gradient. Particles in the air stream 106 within the air channel 102 may be directed away from an interior region of the air channel 102 in the particle discriminator 130 towards a periphery of the air channel 102.

As shown in FIG. 11B, particles 1152, 1154, 1156 and 1158 with increasing particle size are thermophoretically forced towards an interior region of the air stream 106 in the particle concentrator 120 and then are deflected away from the interior region of the air stream 106 in the particle discriminator 130 towards a periphery of the air stream 106, with smaller particles undergoing greater deflection than larger particles. In FIG. 11B, smallest particle 1152′ is deflected and strikes a wall 104 of the particle discriminator 130 before the particle detector 134; small particle 1154′ strikes and is collected on a surface of the particle detector 134; large particle 1156′ is not collected by the particle detector 134 and continues in the air stream 106; and largest particle 1158′ continues in the air stream 106 with less deflection than smaller particles.

FIGS. 12A-12B illustrate a top view and a side view of a system 1200 for analyzing particles in an air stream 106. System 1200 includes an inlet 110, a thermophoretic particle concentrator 120 and a thermophoretic particle discriminator 130. The thermophoretic particle concentrator includes an air channel 102 between channel walls 104 having a first open end for an inlet air stream 112 and a second open end for an outlet air stream 118. The air channel 102 is enclosed by channel wall 104 extending from at least the first open end to the second open end. Two or more heater elements 122 a, 122 b may be positioned between the first open end and the second open end and are positioned near a periphery of the air channel 102. A cross-section of the air channel 102 and channel wall 104 perpendicular to the air stream 106 is rectangular, and at least two heater elements 122 a, 122 b are positioned on two opposing sides of the channel wall 104. The heater segments 1222 a of heater elements 122 a, 122 b extend along the channel wall 104 in a direction substantially parallel to the air stream 106. The particle discriminator 130 including one or more heater elements 132 and particle detectors 134 is coupled to the air channel 102 in a direction downstream from the particle concentrator 120.

FIGS. 13A-13B illustrate a perspective view and a side view of a system 1300 for analyzing particles. System 1300 includes an inlet 110, a thermophoretic particle concentrator 120 and a particle discriminator 130. Thermophoretic particle concentrator 120 includes a pair of thermophoretic heater elements 122 a, 122 b positioned near a periphery of an air channel 102. The thermophoretic heater elements 122 a, 122 b are configured to thermophoretically force airborne particles in the air channel 102 away from the periphery and towards an interior region of the air channel 102 and air stream 106. The channel walls 104 and the cross-sectional geometry of the air channel 102 may be rectangular. Channel walls 104 include portions of a lower wall 1312, side walls 1314, 1316 and upper wall 1318. The perspective view shown in FIG. 13A has the upper wall 1318 removed for clarity. An inlet air stream 112 enters an opening in the channel walls 104 upstream of the particle concentrator 120 and exits an opening in the channel walls 104 downstream of the particle discriminator 130. The thermophoretic heater elements 122 a, 122 b may include one or more heater wires 1322 a, 1322 b, 1322 c suspended in the air channel 102 with heater posts 1326 a, 1326 b. In some implementations, the heater wires 1322 a, 1322 b, 1322 c may be formed into a wire mesh. Alternatively, heater elements 122 a, 122 b may be constructed of thin, partially conductive films on the interior surfaces of electrically insulated channel walls, ceilings, and floors. Electrical current may be sent through heater wires 1322 a, 1322 b, 1322 c to generate the desired thermal gradient.

One or more of the heater wires 1322 a, 1322 b, 1322 c of heater elements 122 a, 122 b may be angled with respect to the air channel 102 in an inward direction along the air channel 102 and towards an interior region of the air stream 106. The thermophoretic heater elements 122 a, 122 b are configured to thermophoretically force airborne particles in the air channel 102 away from the periphery and towards an interior region of the air channel 102 and air stream 106. The thermophoretic heater elements 122 a, 122 b allow focusing of particles in the inlet air stream 112 into a tighter beam of particles with higher particle concentration. Some of the dimensions of the air channel 102 in the region of the particle concentrator 120 may be narrowed to further direct the particles into a narrower beam.

System 1300 includes a particle discriminator 130 with at least one heater element 132 and at least one particle detector 134 positioned on a lower wall 1312 downstream of the particle concentrator 120 to collect and detect particles in the air stream 106. Heater element 132 may include a heater wire 1332 suspended in the air channel 102 with heater posts 1336 a, 1336 b. The dimensions of the walls 104 within the particle discriminator 130 may be narrowed to further concentrate the particles and to increase the magnitude of the thermal gradient that results in an increase of the thermophoretic forces acting on the particles. In some implementations, dimensions of the channel walls 104 in other directions may be widened to slow the speed of airborne particles and allow more time for the thermophoretic heater elements 132 to force and deflect the particles onto the particle detector 134.

In some implementations, the three-dimensional structure of the air channel 102 and/or the configuration of the various individually controlled focusing heaters and precipitation heaters may include individually controlled focusing and precipitating heaters located on the top, bottom, and sidewalls of the air channel 102 to produce a more versatile type of airflow particle detecting device. This device may be reconfigured according to local conditions and particle monitoring objectives. Such reconfiguration may be facilitated by use of suitable processors and control software to control the operation of the various heater elements, particle detectors, and airflow management devices. The effective shape of the flow channels constraining the particulate matter may be programmable to allow compensation for changes in various environmental variables such as air pressure, temperature, and humidity.

FIGS. 14A-14D illustrate top and side views of a system 1400 with a rectangular air channel 102 for analyzing particles in an air stream 106 and operation thereof. An air stream 106 enters a rectangular air channel 102 from an inlet air stream 112, traverses the air channel 102 through a thermophoretic particle concentrator 120 and a thermophoretic particle discriminator 130, and exits the air channel 102 through an outlet air stream 118. Particle concentrator 120 includes a pair of heater elements 122 a, 122 b positioned on one side of the air channel 102 and another pair positioned on an opposite side of the air channel 102. Each heater element 122 a, 122 b may have multiple heater segments 1422 a, 1422 b, 1422 c with heater segments 1422 a and 1422 c extending along the channel wall 104 in a direction substantially parallel to the air stream 106 and heater segments 1422 b extending along the channel wall 104 in a direction that is angled with respect to the air stream 106. Particle discriminator 130 fluidically coupled to the air channel 102 includes a heater element 132 with heater segments 1432 a extending parallel to the air stream 106 and a heater segment 1432 b extending in a direction perpendicular to the air stream 106 for concentrating and deflecting particles 114 in the air stream 106. A plurality of particle detectors 134 a, 134 b, 134 c may be included in the particle discriminator 130 for collecting, detecting and analyzing particles. Particles 114 traversing the air channel 102 may be concentrated in an interior region of air stream 106 within the thermophoretic particle concentrator 120. Particles 114 traversing the thermophoretic particle discriminator 130 may be deflected and collected on a surface of one of the particle detectors 134 a, 134 b, 134 c for detection and analysis. Additional heater elements (not shown) may be positioned above downstream particle detectors 134 b, 134 c to allow greater control over the generated thermal gradients in the air channel 102 and to allow the downstream heater elements to be operated at a higher temperature than the upstream heater elements so that larger particles passed by the first particle detector 134 a may be forced onto one or more of the downstream particle detectors 134 b, 134 c.

FIGS. 15A-15D illustrate top and side views of a system 1500 with an expanding air channel 102 for analyzing particles 114 in an air stream 106 and operation thereof. Particles 114 may enter system 1500 through an inlet air stream 112 into an inlet 110 and traverse air channel 102 through particle concentrator 120 and particle discriminator 130. The particles 114 may be concentrated within the particle concentrator 120 when heater elements 122 a, 122 b are heated and thermal gradients generated within the air channel 102 thermophoretically force the particles 114 towards an interior region of the air channel 102. Heater elements 122 a, 122 b contain heater segments 1522 a, 1522 b in an expanding region 1560 of the air channel 102 within the particle concentrator 120. Heater segment 1522 b is oriented in a direction substantially perpendicular to the air stream 106 and cooperates with heater segments 1522 a in the expanding region 1560 to concentrate the particles 114 in an interior region of the air stream 106, even as streamlines 108 diverge in the expanding region 1560. Particle discriminator 130 includes a heater element 132 with heater segments 1532 a and 1532 b configured to deflect particles 114 onto one or more particle detectors 134 a, 134 b, 134 c. Heater segments 1532 a, 1532 b may be arranged into a “W” configuration to form a thermal potential well for retaining divergent particles 114 near the center of the air channel 102 and to deflect the particles 114 onto one or more particle detectors 134 a, 134 b, 134 c within the particle discriminator 130. In some implementations, the heater segments 132 a, 132 b of heater element 132 may be configured as a sideward “V” to corral particles in the air stream 102 and to deflect the particles onto the particle detectors 134 a, 134 b, 134 c. In some implementations, the heater segments 1532 a, 1532 b may comprise a plurality of serpentine segments to increase the resistance of the heater element 132 and increase the heater voltage applied across the heater element 132.

The application of an external force such as centripetal force, can, in some implementations, be used to improve the ability to differentiate and discriminate between different particle sizes. FIG. 16 illustrates a top view of a system 1600 for analyzing particles in an air stream 106 including a centrifugal particle separator stage 1660. Particles 114 entering system 1600 in an inlet air stream 112 traverse inlet 110, particle concentrator 120, and centrifugal particle separator stage 1660 having a curved air channel 102 positioned between the particle concentrator 120 and a particle discriminator 130. Particles in the air stream 106 may be spatially separated with smaller, lighter particles staying near an inside of the air channel 102 and larger, heavier particles moving towards an outer portion of the centrifugal particle separator stage 1660. The particle discriminator 130 may include a one- or two-dimensional array of particle detectors 134 configured to detect spatially separated particles from the centrifugal particle separator stage 1660. The system 1600 may further include an airflow expansion stage 1670 positioned between the centrifugal particle separator stage 1660 and the particle discriminator 130. The airflow expansion stage 1670 may have an air channel 102 that widens as the air stream 106 traverses the airflow expansion stage 1670. Particles spatially separated in the centrifugal particle separator stage 1660 may be further separated in the airflow expansion stage 1670 as streamlines within the airflow expansion stage 1670 diverge. Additionally, the air channel 102 within the airflow expansion stage 1670 may widen to slow the air velocity and particle velocity in the air stream 106 as the air stream 106 traverses the airflow expansion stage 1670 to allow more time for thermophoretic forces to act on and deflect the particles.

Prior to entering the centrifugal particle separator stage 1660, particles may be concentrated in an interior region that is somewhat offset from a centerline of the air channel 102 in the centrifugal particle separator stage 1660. The thermophoretic particle concentrator 120 may have heater elements 122 a, 122 b with heater segments 1622 a, 1622 b, 1622 c configured to force particles in the air stream 106 towards an interior region that is offset from the centerline of air channel 102 within the particle concentrator 120 to utilize more of the air channel 102 in the centrifugal particle separator stage 1660. To force particles towards an interior region offset from the centerline, heater segments 1622 a and 1622 c may be extended in a direction parallel to the air channel 102 and air stream 106 with heater segment 1622 c positioned closer to a centerline of the air channel 102 in the particle concentrator 120 and heater segment 1622 b extended in a direction that is angled with respect to the air stream 106.

FIGS. 17A-17B illustrate top and side views of a system 1700 for analyzing particles with a widening air channel 102 and a narrowing channel height. System 1700 includes an inlet 110, a thermophoretic particle concentrator 120 and a thermophoretic particle discriminator 130.

The thermophoretic particle concentrator 120 includes an air channel 102 between channel walls 104 having a first open end for an inlet air stream 112 and a second open end for an outlet air stream 118. The air channel 102 is enclosed by channel walls 104 extending from at least the first open end to the second open end. Two or more heater elements 122 a, 122 b each having at least one heater segment 1722 a may be positioned between the first open end and the second open end and near a periphery of the air channel 102. The cross-sectional geometry of the air channel 102 and channel wall 104 perpendicular to the air stream 106 is rectangular, and at least two heater elements 122 a, 122 b having at least one heater segment 1722 a are positioned on two opposing sides of the channel wall 104. The heater segments 1722 a of heater elements 122 a, 122 b extend along the channel wall 104 in a direction substantially parallel to the air stream 106.

The particle discriminator 130 including heater element 132 and particle detectors 134 a, 134 b, 134 c is coupled to the air channel 102 in a direction downstream from the particle concentrator 120. The width of the air channel 102 increases and the height of the air channel 102 decreases in the downstream direction within the particle discriminator 130, allowing the airstream velocity and particle velocity to slow and the thermal gradient to increase in the vicinity of the particle detectors 134 compared to a cross-sectional geometry of constant dimensions. Extended heater segments 1732 a of heater element 132 extend in a direction nominally parallel to the air stream 106 and are configured to retain or further concentrate particles in an interior region of the air stream 106, even as the air channel 102 widens. Heater segment 1732 b of heater element 132 extends in a direction nominally perpendicular to the air stream 106 near the particle detectors 134 a, 134 b, 134 c to allow deflection, collection, detection and analysis of particles in the air stream 106. The cross-sectional geometry of the air channel 102 within the particle discriminator 130 such as the channel height may be narrowed as the air stream 106 traverses the particle discriminator 130. The narrower region of the air channel allows less distance between the heater segments 1732 b and the particle detectors 134 a, 134 b, 134 c, which may result in a higher thermal gradient and a larger thermophoretic force to be generated on particles traversing the narrowed region.

In operation, smaller particles 1714 a, 1714 b that are concentrated in the particle concentrator 120 may be deflected in the particle discriminator 130 by thermal gradients generated by heater segments 1732 a, 1732 b of heater element 132 and collected on a surface of a particle detector 134 a. Larger particles 1714 c, 1714 d that are concentrated in the particle concentrator 120 may then be deflected by thermal gradients generated by heater segments 1732 a, 1732 b of heater element 132 and collected on a surface of a particle detector 134 b or particle detector 134 c. Controlling the velocity of the air stream 106 and the thermal gradients generated in the particle discriminator 130 allow for selective deflection and collection of particles in a particular particle size range onto a surface of one of the particle detectors 134 a, 134 b, 134 c.

FIGS. 18A-18B illustrate top and side views of a thermophoretic particle detection system 1800 for analyzing particles 114 including a pair of multi-tapped heater elements 122 a, 122 b extending through the particle concentrator 120 and the particle discriminator 130. An air channel 102 enclosed by channel walls 104 extends through the inlet 110, particle concentrator 120 and particle discriminator 130. The multi-tapped heater elements 122 a, 122 b have heater segments 1822 a, 1822 b, 1822 c extending through the particle concentrator 120 and additional heater segments 1822 d extending through the particle discriminator 130. Stub heater segments 1822 e may be provided to allow additional control over the temperature profile and thermal gradients generated in the air channel 102 and air stream 106. Heater segments 1822 d extend nominally parallel to the air stream 106 in the particle discriminator 130 whereas heater segments 1832 a, 1832 b, 1832 c extend in a direction nominally perpendicular to the air stream 106 on a side opposite the particle detectors 134 a, 134 b, 134 c to allow deflection, collection, detection, and analysis of particles entering through the inlet air stream 112.

Heater taps 1828 a through 1828 n provide electrical connections to the various heater segments in heater elements 122 a, 122 b for selective application of electrical power to allow control over the heat generated by each heater segment and the thermal gradients generated in the air channel 102. Controlling the velocity of the air stream 106 and the thermal gradients generated in the particle concentrator 120 and the particle discriminator 130 allows for selective concentration, deflection, and collection of particles 114 onto a surface of one of the particle detectors 134 a, 134 b, 134 c. The multi-tapped heater elements 122 a, 122 b allow continuous heater segments, local temperature zone control, a configurable temperature profile, reduced electrical leadout requirements, and a flexible target particle response. In some implementations, multi-tapped heater elements 122 a, 122 b may comprise a thermally isolated wall-mounted thin-film heater element with a polymeric barrier layer that serves as a channel wall for the air channel 102. In some implementations, one or more heater segments of heater elements 122 a, 122 b may be modulated with a varying voltage to allow controlled scanning of particles 114 in a longitudinal direction or a lateral direction with respect to the air stream 106 so that particles of a selected particle size range may be collected on one of the particle detectors 134 a, 134 b, 134 c. Modulation of voltages applied across stub heater segments 1822 e and to deflection heater segments 1832 a, 1832 b, 1832 c may aid in particle selection, deflection, fractionation, detection, and collection uniformity improvements.

The service lifetime of thermophoretic particle detection system 1800 may be extended by controlling and limiting the amount of particulate matter collected on the surface of the particle detectors 134 a, 134 b, 134 c. For example, particle detector 134 a may be operated in conjunction with overlying deflection heater segment 1832 a to collect particulate matter while particle detectors 134 b, 134 c and associated heater segments 1832 b, 1832 c remain in an off condition. After a selected time period of seconds, minutes, hours or days depending on the application, particle detector 134 a and deflection heater segment 1832 a may be turned off and particle detector 134 b with deflection heater segment 1832 b may be turned on and put into operation. After another selected time period, particle detector 134 b and deflection heater segment 1832 b may be turned off and particle detector 134 c with deflection heater segment 1832 c may be put into operation, and so forth. In this manner, the power applied to each of the heater segments 1832 a, 1832 b, 1832 c may be controlled to allow scanning of the deflected particles toward a peripheral wall and onto a surface of the particle detectors 134 a, 134 b, 134 c. Power (e.g. electrical power) applied to one or more of the heater segments 1822 c, 1822 d or 1822 e may be controlled to deflect particles in a lateral direction along the peripheral wall. In some implementations, the incremental change in the resonant frequency or the shift in frequency from a baseline value for resonant-based particle detectors may be used to determine which pair of particle detectors and heater segments are operated and for how long.

FIG. 19 illustrates a block diagram of a system 1900 for analyzing particles in an air stream. Particle detection system 1900 includes a controller 1910 with one or more processors and circuitry for running program code and executing instructions to analyze particles in an air stream among other functions. Controller 1910 may be connected via a communications bus 1940 to one or more memories 1912. Memory 1912 may include a combination of volatile and non-volatile memory for storing program instructions and data. Controller 1910 may communicate with other processors and data systems external to system 1900 via one or more wireless communication links 1914 and antennas 1916 or one or more wired communication links 1918 and external communication lines 1920 such as Ethernet or USB connections. One or more power sources 1922 and ground lines 1924 such as batteries or AC/DC power connections may provide local regulated power for devices connected to bus 1940. Various sensors 1926 and transducers such as temperature sensors, pressure sensors, humidity sensors, accelerometers, gyroscopes, ambient light sensors, clocks, microphones, and speakers may be connected to controller 1910 via communications bus 1940.

One or more particle detection modules 1930 for detecting particles in an air stream may include an inlet air stream 112 for incoming sample air and an outlet air stream 118 for outgoing air. The particle detection module 1930 may include one or more inlets, thermophoretic particle concentrators, and thermophoretic particle discriminators. The air stream within the particle detection module 1930 may be encompassed by the walls of an air channel extending from a first open end for the inlet air stream to a second open end for the outlet air stream. The particle detection module 1930 may be connected to controller 1910 via communications bus 1940 or other dedicated control and/or data lines. Controller 1910 may send control signals to control the power applied to various heater elements coupled to the air stream in the particle detection module 1930. Controller 1910 may be coupled to one or more air movement devices for controlling the movement of air through the air channel.

In some implementations, controller 1910 may provide one or more control signals to particle detection module 1930 to generate and adjust thermal gradients in the air stream. For example, thermal gradients in the air stream may be adjusted by adjusting power applied to one or more heater elements that generate the thermal gradient or by adjusting an airstream velocity of the air stream in the air channel.

FIG. 20 shows a block diagram of a method 2000 for analyzing particles in an air stream. The method 2000 includes applying power to heater elements positioned on various sides of an air channel encompassing at least a portion of the air stream, as shown in block 2005. Power may be applied to one or more pairs of heater elements that may be positioned near a periphery and on opposite sides of the air channel. In some implementations, the entire length of the air channel in the thermophoretic particle concentrator functions as a heater. In other implementations only short portions of the air channel function as a heater. In other implementations, sets or arrays of heater elements may be employed at certain sections of the air channel. These heater elements may operate at different temperatures and may be individually addressed in order to provide a high degree of flexibility in the generated thermal gradient.

In some implementations, the power to the heater elements may be duty cycled (turned on and off) to extend the lifetime of system components. In many use cases, the time constant associated with any significant change in particulate matter concentration is on the order of tens of seconds to minutes or hours or more. Since air quality measurements may only be needed to be conducted once every few seconds or few minutes, or every few hours, there may be extended periods of time during which sampling of particulate matter may be turned off.

Air may be drawn through the air channel, as shown in block 2010. The drawn air may generate the air stream within the air channel. Air may be drawn through the air channel using any one of a variety of air movement devices such as a pump, blower, fan, turbine, motorized air intake device, bellows pump, membrane pump, peristaltic pump, piston pump, positive-displacement pump, rotary vane pump, Venturi device, airflow management device, or other air drawing means for moving or drawing air through the air channel. Drawing air through the air channel may be performed with a duty cycle corresponding approximately with the duty cycling of the heater elements.

Thermal gradients may be generated within the air channel, as shown in block 2015. Heat from electrical power applied to the heater elements combined with airflow profiles and air channel geometries generate one or more thermal gradients within the air channel, resulting in thermophoretic forces on particles in the air stream directed mainly towards the interior or center of the air stream.

Particles in the air stream may be forced away from the periphery of the air channel and towards an interior region of the air channel with the thermophoretic force generated by the thermal gradient to concentrate the particles in an interior region of the air stream, as shown in block 2020. Aerosol particles introduced into the inlet of the air channel may be distributed somewhat randomly throughout the cross-sectional area of the air stream. Action by the thermophoretic particle concentrator may reduce the physical cross-section and narrow the distribution of the particles flowing in the air stream as the air stream and the particles traverse the particle concentrator through the use of controlled thermal gradients. Particle concentration may be achieved through the use of opposing thermophoretic forces aligned with respect to one or more axes of the air channel.

The generated thermal gradients are dependent in part on the loss of heat into the air stream. The air stream in the air channel may exhibit a velocity gradient as a function of distance from the channel wall and length down the channel. Since the amount of heat removed is a function of the local velocity of air in the air stream, the generated thermal gradients are functionally dependent on the airstream velocity profile.

Particles concentrated in the air stream may be detected, as shown in block 2025. In some implementations, particles may be detected by deflecting the particles with generated thermophoretic forces to direct particles in the air stream away from the interior region of the air channel and towards one or more particle detectors positioned on a wall of the air channel, where the particles may be collected on a surface of the particle detector and cause a change in a resonant frequency of the particle detector in response to the mass loading on the surface. In some implementations, the change in resonant frequency over a fixed time may be determined as an indication of the effective mass added onto the surface of the particle detector. In some implementations of particular benefit in environments with a large particulate matter concentration, an adaptive cycle may be used that measures the time to deposit particulate matter on a resonant-based particle detector for a predetermined frequency shift. The system may use at least one processor and be under software control so that when the air particle density is high, the unit may sample less frequently in order to extend the lifetime of the sensor.

In some implementations, the thermal gradients in either the particle concentrator or the particle discriminator may be modulated by modulating the power to the associated heater elements. Modulation of the thermal gradients may spread out the deposition of particles on the particle detectors to avoid non-uniform deposition and to extend the lifetime of the particle detectors.

The detected particles in the air stream may be analyzed, as shown in block 2030. One or more algorithms may be applied to detect the frequency shift of the resonant particle detector and to compensate for temperature effects. The algorithm may apply calibration coefficients and various model parameters to determine an effective mass of the particles collected on the surface of the particle detector and to generate an aerosol mass concentration estimate for the sampled air. In some implementations, the aerosol mass concentration may be estimated for one or more selected particle size ranges.

FIG. 21 shows a block diagram of a method 2100 for analyzing particles including the generation of an aerosol mass concentration estimate. Method 2100 includes concentrating particles in an interior region of an air stream, as shown in block 2105. Particles in the air stream may be concentrated with a thermophoretic concentrator having a plurality of heater elements. The particles may traverse the thermophoretic concentrator and enter a thermophoretic particle discriminator. The thermophoretic particle discriminator may have one or more heater elements. The thermal gradient within the particle discriminator may be controlled, as shown in block 2110. The thermal gradient may be generated and controlled by controlling the amount of electrical power applied to each of the heater segments and heater elements, while accounting for the airstream velocity in the air stream.

An airstream velocity of the air stream within the particle discriminator may be controlled, as shown in block 2115. The airstream velocity may be controlled and adjusted as needed by sending control signals and controlling the power to an air movement device normally positioned downstream and fluidically coupled to the air channel encompassing the air stream. For example, increasing the flow rate of gas through the air movement device increases the airstream velocity and velocity distribution of air or other gas drawn through the air channel.

Method 2100 may include deflecting the concentrated particles in the air stream with a generated thermal gradient, as shown in block 2120. Smaller particles in the air stream may be selectively deflected away from the interior region and towards a periphery of the air stream at a different rate than larger particles in the air stream. The thermal gradient generated in the particle discriminator may be controlled to deflect particles in a selected particle size range onto a surface of one or more particle detectors. Deflected particles within a selected particle size range may be collected on a surface of a particle detector, as shown in block 2125. The selected particle size range may include one of a particle size range between about 0.01 microns and 0.1 microns, 0.01 microns and 0.3 microns, 0.1 microns and 1.0 microns, 1.0 microns and 2.5 microns, 2.5 microns and 10.0 microns, and 10.0 microns and larger. The particle detector may be one or more of a bulk acoustic wave (BAW) resonator, a thin-film bulk acoustic wave resonator (FBAR), a solidly mounted resonator (SMR), a quartz crystal microbalance (QCM), a wall-mounted particle detector, a time-of-flight detector, a resonant sensor, a capacitive sensor, an infrared sensor, an optical sensor, a UV sensor, or a particle mass detector.

Implementations with more than one precipitation heater element may operate in a configuration with a plurality of spatially separated precipitation heating zones, each configurable to operate at the same or different temperatures. The precipitation heat gradients in each precipitation heating zone may be configured to increase as a function of distance along the air channel as the airborne particles continue to move downstream. The smallest particles may be the first to be propelled out of the air stream towards a particle detector when the particles first encounter a low-intensity precipitation heating zone, while medium and larger particles may continue on in the air stream. The larger particles, which may not have been significantly defected during the first, low-intensity precipitation heating zone, may encounter a more intense precipitation heating zone with a higher thermal gradient. Larger particles may be increasingly deflected and propelled towards another particle detector as the larger particles encounter a later, higher intensity part of the precipitation heat gradient. The net effect may further increase the ability to discriminate between airborne particles of different sizes and other characteristics.

An effective mass of the particles collected on the surface of one or more particle detectors may be determined, as shown in block 2130. In some implementations, the effective mass of particles collected on the surface may be the actual mass of the collected particles or a non-normalized estimate of the actual mass. In some implementations, the effective mass may be computed as the difference in mass between a current air sample and an earlier air sample. In some implementations, the effective mass may be normalized to the effective surface area of the particle detector. For example, an estimate of the effective mass may be determined from a form of the Sauerbrey equation that relates changes in frequency of a resonant sensor to the amount of added mass by taking into account the density and elastic moduli of the resonator body, the active surface area of the resonator, and the baseline resonant frequency of the resonator.

An aerosol mass concentration estimate of the particles within the selected particle size range may be generated, as shown in block 2135. For example, the effective mass of particles collected from an air sample may be combined with knowledge of the airflow rate and channel geometry along with the time allocated for sampling to generate the aerosol mass concentration estimate. In some implementations, the aerosol mass concentration estimate may be computed with appropriately scaled multipliers to provide the estimate in the preferred units of micrograms per cubic meter or other selected set of units. In some implementations, the aerosol mass concentration estimate may be generated for particles in the selected particle size range or in a set of selected particle size ranges.

The aerosol mass concentration estimate may be sent or otherwise provided to a requesting entity, as shown in block 2140. In some implementations, the requesting entity may be a user of the particle detection system, an electronic device in communication with the particle detection system, or a database in a cloud-based data center where temporal and spatial aggregations of particulate matter concentrations from a multiplicity of thermophoretic particle detection systems in a geographical region may be maintained over an extended time.

Although the various blocks and steps described in the above process flows and methods are intended to be representative, the steps and the order of the steps may be altered and still remain within the scope, spirit, and claims of this disclosure. Variations in the steps and the order of the steps may be made without loss of generality, such as performing one step before another or combining two or more steps into one step.

While various implementations have been described above, it should be understood that the implementations have been presented by way of example and not limitation. The breadth and scope of the present disclosure should not be limited by any of the implementations described above but should be defined in accordance with the following claims, subsequently submitted claims and their equivalents. 

The invention claimed is:
 1. A method of analyzing particles in an air stream flowing through a chamber comprising walls and an interior region, said particles comprising airborne suspended PM2.5 aerosol particles, the method comprising: separating said PM2.5 aerosol particles according to size by: a) using at least one focusing heater element, disposed on an air stream side of said walls to concentrate particles away from said walls towards said interior region of the air stream, and to produce a beam of focused-concentrated particles; and b) allowing said focused-concentrated particles to progress as a beam though said chamber from an initial focus chamber region at the center of said air stream to a different chamber region at the center of said air stream comprising at least one precipitating heater element; and c) using at least one said precipitating heater element to deflect said focused-concentrated particles in the air stream with a generated thermal gradient; wherein smaller particles in the air stream are selectively deflected away from the interior region and towards a periphery of the air stream at a different rate than larger particles in the air stream, thus producing size-deflected focused-concentrated particles; and detecting said size-deflected focused-concentrated particles within a selected particle size range under 10 microns using a surface of at least one wall-mounted MEMS-based particle detector, wherein said at least one focusing heater element is further angled towards an interior direction of said air stream.
 2. The method of claim 1, further comprising: controlling the generated thermal gradient to deflect said focused-concentrated particles in a selected particle size range onto a surface of said MEMS-based particle detector.
 3. The method of claim 1, further comprising: controlling an airstream velocity of the air stream.
 4. The method of claim 1, wherein the selected particle size range further includes one of particle size ranges between about 0.01 microns and 0.1 microns, 0.01 microns and 0.3 microns, 0.1 microns and 1.0 microns, 1.0 microns and 2.5 microns, and 2.5 microns and 10.0 microns.
 5. The method of claim 1, further comprising: determining an amount of mass of the size-deflected focused-concentrated particles collected on a surface of said at least one wall-mounted MEMS-based particle detector.
 6. The method of claim 5, further comprising: using a velocity or flow rate of said air stream and said amount of mass of said PM2.5 aerosol particles to generate a PM2.5 aerosol mass concentration estimate per unit volume of air of those size-deflected focused-concentrated particles within the selected particle size range; and providing the PM2.5 aerosol mass concentration estimate per unit volume of air.
 7. The method of claim 1, wherein said at least one wall-mounted MEMS-based particle detector is a single wall-mounted MEMS-based particle detector.
 8. A system for analyzing airborne suspended PM2.5 aerosol particles, the system comprising: an inlet; a PM2.5 particle size separator comprising a thermophoretic particle concentrator fluidically coupled to the inlet and a thermophoretic particle discriminator fluidically coupled to said thermophoretic particle concentrator; the system including an air channel for containing an air stream, said air channel comprising walls and an interior, said air channel extending from the inlet through the thermophoretic particle concentrator and through the thermophoretic particle discriminator; said PM2.5 particle size separator comprising a) said thermophoretic particle concentrator disposed on an air stream side of said walls, and configured to concentrate said particles away from said walls of said air channel towards said interior of said air channel, and to produce a beam of focused-concentrated particles; b) said air channel having an interior region configured to enable said focused-concentrated particles to progress as a beam though said air channel from an initial focus interior region at the center of said air channel to a different interior region at the center of said air channel comprising a thermophoretic particle discriminator; c) said thermophoretic particle discriminator configured to deflect and separate said focused-concentrated particles in said air stream according to a size of said particles; and a controller electrically coupled to the thermophoretic particle concentrator and to the thermophoretic particle discriminator, the controller configured to allow: concentrating particles in an interior region of the air stream; and deflecting the concentrated particles in the air stream with a generated thermal gradient; wherein smaller particles in the air stream are selectively deflected away from the interior region and towards a periphery of the air stream at a different rate than larger particles in the air stream, thus producing size-deflected focused-concentrated particles; wherein said controller is further configured to allow: detecting said size-deflected focused-concentrated particles within a selected particle size range under 10 microns on a surface of at least one wall-mounted MEMS-based particle detector, wherein said thermophoretic particle concentrator further comprises at least one focusing heater element angled towards an interior of said air channel.
 9. The system of claim 8, the controller further configured to allow: controlling the generated thermal gradient to deflect particles in a selected particle size range onto a surface of at least one said wall-mounted particle detector.
 10. The system of claim 8, the controller further configured to allow: controlling an airstream velocity of the air stream in the air channel.
 11. The system of claim 8, the controller further configured to allow: determining an amount of mass of the size-deflected focused-concentrated particles collected on the surface of said at least one wall-mounted MEMS-based particle detector.
 12. The system of claim 11, the controller further configured to allow: using a velocity or flow rate of said air stream and said amount of mass of said PM2.5 aerosol particles to generate a PM2.5 aerosol mass concentration estimate per unit volume of air of those size-deflected focused-concentrated particles within the selected particle size range; and providing said PM2.5 aerosol mass concentration estimate per unit volume of air.
 13. A non-transitory computer-readable medium storing computer-readable program code to be executed by at least one processor for analyzing particles in an air stream flowing through a chamber comprising walls and an interior region, said particles comprising airborne suspended PM2.5 aerosol particles, said computer readable program code comprising instructions configured to cause: separating said PM2.5 aerosol particles according to size by: a) causing at least one focusing heater element, which is disposed on an air stream side of said walls to concentrate said particles in an interior region of the air stream; and to produce a beam of focused-concentrated particles; b) wherein said chamber has an interior region configured to enable said focused-concentrated particles to progress as a beam though said chamber from an initial focus chamber region at the center of said air stream to a different chamber region at the center of said air stream comprising at least one precipitating heater element; and c) causing said at least one precipitating heater element to deflect said focused-concentrated particles in the air stream with a generated thermal gradient; wherein smaller particles in the air stream are selectively deflected away from the interior region and towards a periphery of the air stream at a different rate than larger particles in the air stream, thus producing size-deflected focused-concentrated particles; and detecting said size-deflected focused-concentrated particles within a selected particle size range under 10 microns on a surface of at least one wall-mounted MEMS-based particle detector, wherein said at least one focusing heater element is further angled towards an interior direction of said air stream.
 14. The non-transitory computer-readable medium of claim 13, the instructions further configured to cause: controlling the generated thermal gradient to deflect said focused-concentrated particles in a selected particle size range onto a surface of said MEMS-based particle detector.
 15. The non-transitory computer-readable medium of claim 13, the instructions further configured to cause: controlling an airstream velocity of the air stream in an air channel.
 16. The non-transitory computer-readable medium of claim 13, the instructions further configured to cause: determining an amount of mass of the size-deflected focused-concentrated particles collected on said surface of said at least one wall-mounted MEMS-based particle detector.
 17. The non-transitory computer-readable medium of claim 16, the instructions further configured to cause: using a velocity or flow rate of said air stream and said amount of mass of said PM2.5 aerosol particles to generate a PM2.5 aerosol mass concentration estimate per unit volume of air of those size-deflected focused-concentrated particles within the selected particle size range; and providing the PM2.5 aerosol mass concentration estimate per unit volume of air. 